To our knowledge, a single case of intraoral spindle cell hemangioma has appeared in the literature. It has a slow rate of growth and usually reaches 1 to 2 cm. In the oral cavity, the origin of the spindle cell neoplasms may be traced to epithelial, mesenchymal and odontogenic components. In this study, we reported a case of multiple spindle cell hemangioma in both lungs. Oral surgery, oral medicine, oral pathology, oral radiology and endodontology. Otherwise, the spindle cell hemangioma was growth slowly, and the size of nodules was usually 12cm 1, 2.
Spindle cell hemangioma acquired tufted angioma angioblastoma of nakagawa. The mass developed 5 years earlier and enlarged after repeated ethanol injections. These tumors are painful redbrown or bluish lesions that usually appear on the arms or legs. The previous cases of splenic hemangioendothelioma discussed in the literature have similar histopathological and indolent clinical characteristics similar to the forms described at other sites 68. Spindlecell hemangioendothelioma is a vascular tumor that was first described in 1986 by sharon weiss, m. Hemorrhagic epithelioid and spindle cell hemangioma keel. They are characterized by cavernous blood vessels and spindle cell proliferation. Histologic examination revealed a vascular tumor with occasional blister cells and a complex combination of histologic patterns consisting of spindlecell hemangioma, retiform hemangioendothelioma, and epithelioid hemangioendothelioma components, suggestive of che image 1b, image 2a, image 2b, and image 2c. The final diagnosis of sch was made by histopathologic findings. Spindle cell hemangioma sch is a rare benign vascular tumor and we report 2 cases of sch who are 50yearold man and 16yearold girl. Pdf spindle cell hemangioma sch is an uncommon tumor that usually presents as subcutaneous or deep dermal nodule affecting the extremities and is. Spindle cell hemangioma spindle cell hemangioen dothelioma is. There will be clusters of thin walled capillaries in the dermis.
Casereport spindle cell hemangioma in the mucosa of the upper lip. Histopathology of spindle cell vascular tumors surgical. There are no radiologic reports concerning cardiac spindle cell hemangioma in the current literature. Vascular tumors with a spindled morphology represent a diagnostic challenge in soft tissue pathology. Oral surg oral med oral pathol oral radiol endod 2008. Who in 1996 renamed it as spindle cell haemangioma when further data suggested a benign clinical course they occur as solitary nodule or give rise to. The spindlecell hemangioma component is identified by the. In the present case, separate tumors with histologic features of spindle cell hemangioma and features resembling epithelioid hemangioendothelioma were clustered in 1 anatomic region. Primary mediastinal tumours comprise a broad spectrum of neoplastic proliferations deriving from the intrathoracic organs, soft tissues, lymphoid tissue and primitive germ cells. Kaposiform hemangioendothelioma kaposi sarcoma angiosarcoma.
To the best of our knowledge, there are no prior reports of sch in the spleen. Spindle cell hemangioendothelioma of the temporal muscle. We report here a case of cardiac spindle cell hemangioma. Ches are rare vascular tumors in which various types of hemangioendothelioma are combined in 1 lesion. Spindle cell hemangiomas have a biphasic composition. A diagnosis for spindle cell hemangioma includes evaluating the clinical history physical exam and a thorough family history. Epithelioid hemangioendothelioma is a malignant vascular tumour. The anterior mediastinum is the second most common site for. The mass was elastic firm, mobile, bluish in color, and well demarcated in magnetic.
Spindle cell hemangioma sch, first identified by weiss and enzinger in 1986, was initially characterized as a borderline vascular neoplasm and classified as spindle cell hemangioendothelioma. So far, the case of multiple spindle cell hemangiomas in both lungs has not been reported yet in the english literature. The present case was diagnosed as hemangioma by clinical and mri findings at first. Spindle cell hemangioma hemangioendothelioma of the hand and neck. Spindle cell neoplasms are defined as neoplasms that consist of spindle shaped cells in the histopathology. It typically develops as a solitary nodule or multiple masses located in the dermal or subcutaneous layers of the distal extremities. Spindle cell hemangioendothelioma sch was originally described by weiss and enzinger 1986 as a lowgrade angiosarcoma resembling both cavernous hemangioma and kaposis sarcoma.
Case report of lumbar intradural capillary hemangioma. Spindle cell hemangioendothelioma chapter 21 maffucci syndrome chapter 20. Cases were retrieved from the surgical pathology files of the. Only the cells lining the vascular spaces and the epithelioid cells stain for endothelial markers cd31 and cd34. Sch stands for spindle cell hemangioendothelioma pathology. Presentation in the oral cavity is rare with only two previously reported cases. Although the nature of psh is still controversial, its histological feature has been well.
Spindle cell haemangioendothelioma and germinoma of the mediastinum biernat, w 20010601 00. Spindle cell hemangioma sch was an extremely rare benign tumor which typically arised in the subcutis of the distal extremities of young people. We report a case of spindle cell hemangioma that presented as an asymptomatic mass of the buccal mucosa in a 44. A growing amount of evidence indicates that multifunctional ecm molecule decorin regulate endothelial cellmatrix interactions during angiogenesis. Capillary hemangioma is a rare tumor in spinal intradural location. Pyogenic granuloma lobular capillary hemangioma histopathology image 2 path quiz case 70 pathology quiz online. Rare vascular proliferations of the oral mucosa oral surgery, oral. Most schs present as one or more nodules affecting the dermis or subcutis of. Spindle cell hemangioma sch is a distinct benign vascular lesion that typically occurs in the dermis or subcutis of distal extremities. Neuroimagine of the thoracic spine showed an intraspinal, extradural mass lesion, measuring 5. Recent studies suggest that sch is a benign neoplasm or reactive lesion accompanying a congenital or acquired vascular malformation.
The case provides support for recent reports suggesting an association between this peculiar vascular lesion and skeletal enchondromatosis. The increasing immunohistochemical and molecular findings indicate that it originates from primitive respiratory ephithelium4, 5. Clinically, spindle cell hemangioma is a superficial, subcutaneous or dermal erythematous to violaceous nodule with a predilection for the distal extremities of young adults, especially the hands. The usual sites are skin and mucous membranes of head and neck region and are small in size. Spindle cell hemangioma is an uncommon benign vascular tumor of the oral cavity. Since the publication of the seminal work on the histologybased classification of vascular. Spindle cell hemangioma, formerly termed spindle cell hemangioendothelioma, is an uncommon benign vascular tumor. How is spindle cell hemangioendothelioma pathology abbreviated. Spindle cell haemangioma sch is a benign vascular lesion which usually occurs on distal extremities. Histopathology of spindle cell vascular tumors sciencedirect.
Spindle cell hemangioma hemangioendothelioma of the head and neck. To report and discuss a case of sch in an 11yearold boy. Spindle cell hemangioma sch is a distinct benign vascular lesion that typically occurs in the dermis or. Histologically the lesion was a spindle cell haemangioma composed of dilated vascular spaces and a proliferation of bland appearing interspersed spindle cells. Spindle cell lipoma is a rare variety of lipoma that usually appears in subcutaneous tissue, for example, the posterior neck, shoulders, and back region, in middleaged and older males. The case of a 49yearold man with maffuccis syndrome, who developed multiple spindle cell hemangioendotheliomas, is presented. Sch is defined as spindle cell hemangioendothelioma pathology. A 68yearold man had a painless swelling of the floor of mouth. Spindle cell hemangiomas have cells called spindle cells that look long and slender under a microscope. A lowgrade angiosarcoma resembling a cavernous hemangioma and kaposis sarcoma. Multicentric spindle cell hemangioendothelioma of spleen.
Spindle cell hemangioma sch is an uncommon benign vascular tumor. This article focuses on vascular tumors characterized by a predominantly spindled morphology, including spindle cell hemangioma, acquired. Spindle cell hemangioma is an uncommon vascular lesion histologically resembling a cavernous hemangioma and kaposis sarcoma with a predilection for the extremities. The tumour occupies an intermediate position in the spectrum of epithelioid vascular tumours lying between the benign epithelioid hemangioma and the more aggressive epithelioid angiosarcoma. It may be difficult to distinguish certain benign entities in this category from spindled vascular tumors of intermediate malignancy or even spindled variants of angiosarcoma. Sch is now considered a benign vascular tumor or malformation and can occur at. Spindle cell hemangioma sch is a unique benign vascular lesion. Hemangiomas and vascular malformations 371 21 clinical images are available in hardcopy only. Soft tissue, lung formerly known as intravascular bronchioalveolar tumour, pleura, liver, peritoneum, bone, lymph nodes and skin. This website is intended for pathologists and laboratory personnel, who understand that medical information is imperfect and must be interpreted using reasonable medical judgment. The important diagnostic issues include 1 distinguishing spindle cell squamous cell carcinoma and malignant melanoma from true sarcoma, 2 discriminating between benign spindle cell lesions and malignancies, and 3 classifying histologic types and subtypes. This article focuses on vascular tumors characterized by a predominantly spindled morphology, including spindle cell.
Pulmonary sclerosing hemangioma psh is a rare pulmonary tumor, first described by liebow and hubbel. This report deals with histopathological features of these. Other tools to help diagnose the condition may include. The histopathology of ks is essentially identical in the different epidemiologic ks types. Spindle cell hemangioma hemangioendothelioma of the head. Histopathology of spindle cell vascular tumors article pdf available in surgical pathology clinics 102 march 2017 with 1,962 reads how we measure reads. Spindle cell hemangioma hemangioendothelioma is a distinct vascular lesion which was initially considered to be a low grade angiosarcoma when first described in 1986. Hemangioma simplex strawberry mark cavernous hemangioma salmon patch telangiectasia in the superficial dermis.
This is a case report of a woman who had capillary hemangioma of cauda equina. Histologically, all lesions were comprised of lobules of spindle cells that grew. Definition of spindle cell hemangioma nci dictionary of. Spindle cell haemangioma sch was originally described as spindle cell haemangioendothelioma in 1986 by weiss and enzinger and whose behaviour fell between benign haemangioma and malignant angiosarcoma. We present a case of sch in the upper lip of a 41yearold woman. Spindle cell hemangioma in a 21yearold woman with maffucci. Spindle cell haemangioendothelioma and germinoma of the. Pulmonary sclerosing hemangioma presenting with dense. Spindle cell hemangioma in the mucosa of the upper lip. We reported a rare case of spindle cell lipoma of the floor of mouth. Spindle cell hemangioma sch is an uncommon benign vascular neoplasm, histologically characterized. American society for clinical pathology academy of clinical laboratory physicians and scientists. A 19yearold hivnegative female was found to have multiple lung nodules by the chest xray during the physical examination. Spindle cell lipoma histopathology section showing the characteristic features.
In some cases, spindle cell hemangioma presents as multiple smaller nodules. Hemorrhagic epithelioid and spindle cell hemangioma keel 1999. Spindle cell hemangioma sch was first described by weiss and enzinger in 1986. Furthermore, a current publication shows that no detectable decorin expression was found in the stromas of. They presented the initial 26 cases and at the time concluded that the vascular lesion was a vascular tumor of lowgrade malignancy, and therefore, they termed the lesion a spindle cell hemangioendothelioma. Most spindle cells stain only for vimentin and a smaller percent for actindesmin. Spindle cell hemangioma sch is considered a benign vascular lesion. Despite the rarity, early recognition is important because of the risk of hemorrhage. Hemangiomas and vascular malformations 375 21 clinical images are available in hardcopy only.
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